Teddington RFC will be hoping to get a second win to continue their cup campaign as they take on Eastbourne RFC. 

Having gone through the entire league campaign by winning every match, the Antlers won 77-7 in their first cup game against Bognor. 

Eastbourne only lost one game in their league season on route to winning Counties Two Sussex and kept that up by beating Dover 30-24 to start their cup campaign. 

Kick-off at Teddington RFC is at 3pm on Saturday. 

Harlequins will hope to end a three-match losing run as they return to the Twickenham Stoop against Newcastle this weekend. 

Quins exited the European Champions Cup at the hands of Stormers last week and are without a win since the start of March. 

Home form has been the backbone of Quin's form and bottom club Newcastle have won once on the road in the league this season but did break a four-match losing run last time out against Gloucester. 

Kick-off at the Twickenham Stoop is at 3pm on Saturday. 

Ealing Trailfinders are three matches away from RFU Championship glory as their title fight comes down to the wire. 

The Trailfinders are on a seven-match unbeaten run to remain one point ahead of Jersey Reds in the table, ahead of next week's showdown they will hope to remain in the driving seat. 

Caldy are playing for nothing as the season draws to a close and have won just once in their last five, but they did get the better of Ealing in the reverse fixture in January. 

Kick-off at Trailfinders Sports Club is at 3pm. 

London Scottish will be hoping for their second league win of the season as they visit Hartpury University on Friday. 

Scottish have lost their last 11 matches in the league and are yet to be on the winning side this year having been cut adrift at the bottom of the RFU Championship. 

Hartpury are in mid-table obscurity in 7th place in the table and have lost their last four matches to mean they have won nine and lost ten this season. 

Kick-off at the Alpas Arena is at 7:45pm on Friday.